Question

Short/ Long answer type questions.
As a result of an automobile accident, 50 per cent of the muscle fibres in the biceps muscle of a person were destroyed. Ten months late; the biceps muscle was able to generate 80 per cent of its original force. Describe the changes that took place in the damaged muscle that enabled it to recover.

Answer 1

Although the myofibrils are generically considered to be non-mitotic, the regenerative capacity of skeletal muscles is ensured by an intrinsic mechanism. During embryonic development, a reserve pool of undifferentiated cells called satellite cells is stored below the basal lamina of each myofibril. In response to damage, these cells firstly proliferate, then differentiate into myofibrils and finally join with each other to form multinucleated myotubules.