Question

Suppose the correct sequence of nucleotides on a single DNA strand is AGGCTGTTAT. A mutation occurs, and the sequence becomes AGGCATGTTAT. Which of the following types of mutation is this?

• A. Deletion
• B. Insertion
• C. Base substitution
• D. Non-frameshift mutation

Answer 1

The correct option is B Insertion

After the 4th nucleotide base, an extra A has been added, which is the mutation in this case. Since it is the addition of an extra base, the type here is insertion mutation. It is also a type of frameshift mutation, as the reading frame of the sequence has been altered or shifted.