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Question

TAB vaccine is against which of the following diseases?

A
Polio
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B
Pneumonia
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C
Typhoid
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D
Diphtheria
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Solution

The correct option is C Typhoid
The TAB vaccine is popularly known as the typhoid paratyphoid A and B vaccine is a combined preparation of killed pathogens responsible for the typhoid, paratyphoid A and paratyphoid B diseases. The vaccine is no longer used as it could not prevent the occurrence of paratyphoid infection by Salmonella paratyphi.

The principle behind the vaccination is that the antigens in the vaccine would trigger the B and T lymphocytes to produce antibodies and other cytotoxic cells that destroy the antigen. The memory B and T lymphocytes generated in response to the vaccine would launch a faster and stronger immune response against the pathogen in the event of an actual infection in the future. This would prevent the occurrence of the infection.

The pathogen responsible for typhoid fever is Salmonella typhi. This disease is characterised by sustained fever, weakness, stomach pain, constipation, loss of appetite etc. It spreads through contaminated food and water.

These are two types of typhoid vaccines available at present :
  • An oral vaccine containing live attenuated germs
  • An inactivated killed bacterial preparation that is injected into the body.
DTP vaccine is administered to protect against the bacterial diseases diphtheria (Corynebacterium diphtheriae) , tetanus ( Clostridium tetani) and pertussis (Bordetella pertussis). The vaccine consists of killed bacteria that is injected into the muscles of the forearm in children. The children should receive 5 doses of the vaccine.

There are two types of vaccines available for polio. Inactivated polio vaccine (IPV) containing killed polio virus is administered as injections in the arm or leg. Oral polio vaccine (OPV) containing live attenuated virus is administered as oral drops.

The pneumococcal conjugate vaccine (PCV) is used to prevent pneumonia caused by Streptococcus pneumoniae.

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