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The cell cycl...

Question

The cell cycle consists of four major phases $G_{1} (g a p) - > S (D N A s y n t h e s i s) - > G_{2} (g a p) - > M (m i t o s i s)$ . The yeast mutation cdc8 blocks the cell cycle transition from $G_{2}$ phase into M phase. If the DNA content of a normal haploid yeast cell is N, then the DNA content of a haploid cdc8 mutant blocked in $G_{2}$ phase is

A

N

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B

2N

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C

3N

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D

4N

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E

8N

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Solution

The correct option is B 2N
Since cdc8 blocks the transition from G $_{2}$ phase to M phase. Therefore there will be no effect of this mutant on S-phase. Since, DNA synthesis occurs in S-phase, DNA replication takes place normally. Hence, the DNA content of a haploid mutant blocked in G $_{2}$ after doubling will be 2N.
So, the correct answer is '2N'

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