The condition in-which kidneys fail to conserve water leading to water loss and dehydration due to impaired ADH synthesis or release is

Graves disease

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Addisons disease

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Diabetes insipidus

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Cretinism

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Acromegaly

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Solution

The correct option is D Diabetes insipidus
Diabetes insipidus is a condition caused by the deficiency of antidiuretic hormone ADH in the body. ADH(Antidiuretic hormone) helps the kidneys keep the correct amount of water in the body. Diabetes insipidus is marked by intense thirst and heavy urination. Thus the condition in-which kidneys fail to conserve water leading to water loss and dehydration due to impaired ADH synthesis or release is Diabetes insipidus'.
So, the correct answer is 'Diabetes insipidus'.

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