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Question

The enzyme DNA polymerase was discovered by _________.

A
Kornberg
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B
Okazaki
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C
Watson and Crick
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D
Stahl and Meselson
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E
Jacob and Monod
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Solution

The correct option is A Kornberg
Arthur Kornberg purified and characterized DNA polymerase from E. coli cells which are encoded by the polA gene. It catalyzes phosphoryl group transfer. The 3-hydroxyl group of the nucleotide at the 3'-end of the growing strand serves as a nucleophile for nucleophilic attack at the α-phosphorus of the incoming deoxynucleoside triphosphate. Inorganic pyrophosphate is released in the reaction.
So, the correct answer is option A.

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