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Question

The enzyme which helps to cut one strand of DNA duplex to release tension of coiling of two strands is


A
DNA ligase
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B
DNA Polymerase I
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C
Topoisomerase
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D
Swielases (helicase or unwindases)
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Solution

The correct option is C Topoisomerase
Common problems such as overwinding (positive supercoiling), knots, and tangles are resolved by topoisomerases by catalyzing the breaking of one or two strands of DNA. It releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription is done by transiently cleaving and rejoining one strand of the DNA duplex.
Thus, the correct answer is option C.

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