The correct option is A pBR322
The first plasmid to be used was pSC101. This plasmid was obtained from bacteria and modified to be used as vector. However, the first ever articial plasmid was made by two researcher. Boliver and Rodriguez. It was named a pBR322. The p stands for plasmid and the BR stands for the two scientists who worked on it. 322 is the batch number of the plasmid.