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Question

The first recombinant DNA was constructed by linking an antibiotic-resistant gene with the native plasmid of

A
Escherichia coli
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B
Salmonella typhimurium
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C
Clostridium butylicum
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D
Acetobacter aceti
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Solution

The correct option is B Salmonella typhimurium
The construction of first recombinant DNA emerged from the linking of the gene encoding antibiotic resistance gene with a native plasmid of Salmonella typhimurium.
It was accomplished by Stanley Cohen and Herbert Boyer in 1972. They isolated the antibiotic resistance gene by cutting out a piece of DNA. This cutting of DNA at specific locations is carried out by molecular scissors also known as restriction enzymes.

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