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Question

The human genome project involves all of the following except _________.

A
Altering the human genome
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B
Physical mapping of the chromosomes
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C
Sequencing of the entire nucleotide sequence of the human genome
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D
Location of RFLP markers
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Solution

The correct option is A Altering the human genome
The Human Genome Project (HGP) was launched on 1st October 1990 for sequencing the entire genome. This project had the following objectives:-
  • To identify all the approximately 20,000-25,000 genes in human DNA.
  • To determine the sequences of the 3 billion base pairs that make up human DNA.
  • Knowing locations of RFLP markers. Restriction fragment length polymorphism (RFLP) is a technique that exploits variations in homologous DNA sequences. The principle of RFLP markers is that any genomic DNA can be differentiated according to the presence or absence of restriction enzyme sites.
  • Mapping the presence of genes on different chromosomes.
So, the correct option is 'altering the human genome'.

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