Question

The inhibitory effect of malonic acid on succinic dehydrogenase enzyme is

• A. Competitive inhibition
• B. Non-competitive inhibition
• C. Feedback inhibition
• D. Inhibition due to end product

Answer 1

The correct option is A Competitive inhibition

Competitive inhibitor resembles the natural substrate and combines reversibly to the free enzyme at the active site. Thus, there is a competition between substrate and inhibitor for the active site of the enzyme. e.g., malonate inhibits succinate dehydrogenase activity because its structure is similar to succinate.

So, the correct answer is option A.