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Question

The intermediate product between α-ketoglutaric acid and succinic acid in TCA cycle is

A
Acetyl CoA
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B
Succinyl CoA
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C
Fumarate
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D
Oxalosuccinic acid
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Solution

The correct option is B Succinyl CoA
Succinyl CoA is an important intermediate in the citric acid cycle, where it is synthesized from α-ketoglutarate by α-ketoglutarate dehydrogenase through decarboxylation. During the process, coenzyme A is added. Succinyl-CoA is an intermediate of the citric acid cycle and can be readily incorporated there. Thus, the correct answer is 'Succinyl-CoA.'

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