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Nucleosome

The length of...

Question

The length of DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is this DNA accomodated?

A

Through elimination of repetitive DNA

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B

Deletion of non-essential genes

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C

Coiling of nucleosomes

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D

DNase digestion

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Solution

The correct option is C Coiling of nucleosomes
Since the length of DNA molecule is manyfold greater than the length of the eukaryotic cell, the cell packages the DNA molecule along with packaging proteins called as histones. This leads to the supercoiling of DNA around the histones to form nucleosomes, and this greatly decreases the length of the DNA molecule, fitting it inside the eukaryotic cell.

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Q. The length of DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is this DNA accommodated?

Q. In the eukaryotes the DNA molecules are organised withing the nucleus. How is the DNA molecules organised in a bacterial cell in the absence of nucleus?

Q. Assertion: Eukaryotic genome is classified into highly repetitive, moderately repetitive, and single-copy DNA on the basis of reiteration.
Reason: Reassociation kinetics of repetitive DNA is slower than the non-repetitive DNA.

Q. How are the following formed and involved in DNA packaging in a nucleus of a cell?
(i) Histone octomer (ii) Nucleosome (iii) Chromatin.

Q. In the eukaryotic genome
(A) Repetitive DNA is represented as a different peak in density gradient centrifugation
(B) The classification of microsatellite and minisatellite is based on the base composition, length of the segment, and number of repetitive units
(C) Coding DNA forms a large portion of the human genome
(D) Repetitive DNA shows high degree of polymorphism

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