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Question
The length of DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is the DNA accommodated?
The length of DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is the DNA accommodated?
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Solution
The correct option is D Super-coiling in nucleosomes.
Histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds and play a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long (a length to width ratio of more than 10 million to 1 in human DNA). For example, each human cell has about 1.8 meters of DNA, (approx. 6 ft) but wound on the histones it has about 90 micrometers (0.09 mm) of chromatin, which, when duplicated and condensed during mitosis, result in about 120 micrometers of chromosomes. So, DNA is accommodated by super-coiling in nucleosomes.
Histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds and play a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long (a length to width ratio of more than 10 million to 1 in human DNA).
For example, each human cell has about 1.8 meters of DNA, (approx. 6 ft) but wound on the histones it has about 90 micrometers (0.09 mm) of chromatin, which, when duplicated and condensed during mitosis, result in about 120 micrometers of chromosomes. So, DNA is accommodated by super-coiling in nucleosomes.
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