The correct option is D 10!4!3!11P22!
The word INDEPENDENCE has 4E,2D,3N and I,P,C
that is EEEEDDNNNIPC
now let's permute all the words other than D.This can be done in 10!4!×3! ways.
now the placing of these 10 words creates 11 gap.So any 2 of these gap can be chosen to fill the Ds.This can be done in (112) ways.
Hence no. of words in which Ds don't come together are 10!4!×3!×(112)
Hence, option 'D' is correct.