Question

The model that an enzyme interacts with only a specific substrate is explained by

• A. Enzyme-substrate concept
• B. Destroyed and resynthesized concept
• C. Lock and key concept
• D. Activation energy concept

Answer 1

The correct option is C Lock and key concept

Enzymes are specific in their action. The enzymes combine with the substrate to form an enzyme-substrate complex. Part of an enzyme where substrate molecules get attached is known as an active site. On attachment to the active site, the substrate is changed into the product. The active site has a residue which helps in the attachment of substrate. The substrate molecules form a temporary bond with the enzyme at the active site. The size and shape of the substrate determine its attachment to the active site. Lock and the key model was given by Emil Fischer in 1894. It states that the specific substrate attaches to an active site like a key fits in a specific lock.

So, the correct answer is option C.