Question

The nucleus establshes a communication pathway with the cell membrane by the help of which organelle?

Answer 1

the critical function of the nuclear membrance is to act as a barrier that seprates the contents of the nucleus from the cytoplasam. Like other cell membrance, the nuclear membrance are phospholipid bilayers, whic are permamble only to small nonpolar molecules.
Underlying the inner nuclear membrane is the nuclear lamina, a fibrous meshwork that provides structural support to the nucles. The nuclear lamina is composed of one or more relatedproteins called lamina. Most mammalian cells, for example, contain four differentlaminas designated A, B1 B2 and C. All the lamins are 60- to 80-kilodalton (kd) fibrous proteins that are related to the intermediate filament proteins of the cytoskeleton. Like other intermediate filament proteins, the lamins associate with each other to form filaments . The first stage of this association is the interaction of two lamins to form a dimer in which the α-helical regions of two polypeptide chains are wound around each other in a structure called a coiled coil. These lamin dimers then associate with each other to form the filaments that make up the nuclear lamina. The association of lamins with the inner nuclear membrane is facilitated by the posttranslational addition of lipid—in particular, prenylation of C-terminal cysteine residues . In addition, the lamins bind to inner nuclear membrane proteins, which may help organize the lamin filaments into a meshwork and mediate their attachment to the membrane.