Question

The order of reactivity of the following substrates in a nucleophilic addition reaction is:

• A. $\left(iv\right)>\left(iii\right)>\left(ii\right)>\left(i\right)$
• B. $\left(ii\right)>\left(i\right)>\left(iii\right)>\left(iv\right)$
• C. $\left(ii\right)>\left(iv\right)>\left(i\right)>\left(iii\right)$
• D. $\left(ii\right)>\left(i\right)>\left(iv\right)>\left(iii\right)$

Answer 1

The correct option is D $\left(ii\right)>\left(i\right)>\left(iv\right)>\left(iii\right)$

`-I` and `-M` groups increase the reactivity of carbonyl group whereas `+I` and `+M` groups decrease the reactivity of carbonyl groups towards nucleophilic addition.