Question

The oxygen - haemoglobin dissociation curve will show a right shift in case of

• A. High $pC{O}_2$
• B. Less $H^{+}$ concentration
• C. High $p{O}_2$
• D. Low $pC{O}_2$

Answer 1

The correct option is A High $pC{O}_2$

Oxygen dissociation curve :

The graph depicting the percentage of saturation of oxyhaemoglobin at various partial pressures of oxygen is known as the oxygen dissociation curve. The curve displays the equilibrium of oxyhaemoglobin and haemoglobin at various partial pressures.


Rightward shift of curve :

Shifting of the curve towards the right indicates that higher partial pressure of oxygen is required for achieving a particular percentage of oxygen-saturated hemoglobin.
The oxygen haemoglobin curve is shifted to the right when there is high $H^{+}$ concentration/ low $pH$ and high temperature. Higher $C{O}_2$ concentration makes the $pH$ acidic and hence, the curve is shifted to the right.

Leftward shift of curve :

A shift of the curve to the left indicates that lower partial pressure of oxygen is required for achieving a particular percentage of oxygen-saturated hemoglobin.
The oxygen haemoglobin curve is shifted to the left when there is low $H^{+}$ concentration/ higher $pH$ and low temperature.

Final answer : a. High pCO2