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Question

The point mutations A to G, C to T, C to G and T to A in DNA are

A
Transition, transition, transversion and transversion respectively
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B
Transition, transversion, transition and transversion respectively
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C
Transversion, transversion, transition and transition respectively
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D
All four are transition
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Solution

The correct option is B Transition, transition, transversion and transversion respectively
Point mutations or base pair mutations are of two types:
1. Transitions: When a purine base is replaced by another purine base and pyrimidine is replaced by another pyrimidine base. For example, Adenine (A) to Guanine (G) or Cytosine (C) to Thymine (T).
2. Transversion: When a purine base is replaced by a pyrimidine base and vice versa. For example, Adenine (A) to Thymine (T) or vice versa and Guanine (G) to Cytosine (C).
Hence A to G and C to T are transitions and C to G and T to A are transversions. So, the correct answer is 'Transition, transition, transversion and transversion respectively'.

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