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Question

The presence of checkpoint during mitosis ensures the attachment of all chromosomal kinetochore proteins to the spindle fibres. The absence of attachment of kinetochore proteins produces a signal preventing mitosis to proceed to next stage. The occurrence of this check point is responsible for transition from

A
Anaphase to telophase
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B
Prophase to metaphase
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C
Metaphase to telophase
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D
Prophase to anaphase
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E
Metaphase to anaphase
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Solution

The correct option is C Metaphase to anaphase
The attachment of all chromosomal kinetochore proteins to the spindle fibres to facilitate their arrangement on cell's equator takes place during mitosis. The failure of this process signal the checkpoint to prevent the transition of metaphase into anaphase as metaphase of mitosis is followed by anaphase.
So, the correct answer is option E.

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