Question

The process used in conversion of pyruvate to acetyl CoA is

• A. Oxidative dehydration
• B. Oxidative decarboxylation
• C. Oxidative phosporylation
• D. Oxidative dephosphorylation
  
• E. None of the above

Answer 1

Answer: (B)

Oxidative decarboxylation

Pyruvate decarboxylation or oxidative decarboxylation reaction is the far from equilibrium biochemical reaction that uses pyruvate to form acetyl-CoA, releasing NADH, a reducing equivalent, and carbon dioxide via decarboxylation. This reaction is very common in most organisms as a link between glycolysis and the citric acid cycle. So, the process used in conversion of pyruvate to acetyl CoA is oxidative decarboxylation. Thus, option B is correct.