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Question

The reaction of O2 and CO with haemoglobin gives:

A
Only oxygen-haeme complex
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B
Only CO haeme complex
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C
Both but oxygen-haeme-complex is more stable
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D
Both but CO haeme-complex is more stable
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Solution

The correct option is B Only CO haeme complex
When carbon monoxide binds to hemoglobin, it shifts the entire oxygen-hemoglobin curve not only to the left but also down. The leftward shift takes place because when carbon monoxide binds to the hemoglobin, it makes the other unoccupied heme groups much more likely to bind to oxygen (increases its affinity).

Hence B is correct answer


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