Question

The schematic above shows a typical cell cycle progression. The diamond marks the position of a vital checkpoint in cell cycle control. What would be a consequence of a malfunction at this checkpoint?

• A. Inability to progress beyond metaphase
• B. Interrupted cytokinesis
• C. Production of aneuploid cells
• D. Incomplete DNA replication

Answer 1

The correct option is A Inability to progress beyond metaphase

The check point at the M phase is last check point of the cell cycle. This is also referred to as the spindle check point because with any defect during the earlier phases of the cell cycle the spindle apparatus formation does not take place and the cell cycle is arrested at Metaphase.

So, the correct answer is 'Inability to progress beyond metaphase'