Question

The signal transduction of steroid hormone across cell is through

• A. Binding of hormone to the cytoplasm receptor and the complex binds to hormone response element on DNA within promoter DNA
• B. Binding of hormone to the transmembrane receptor which initiates the production of the second messenger that activates enzymes which further activates transcription factors
• C. Binding to hormone to the transmembrane receptor which diffuses inside the cell cytoplasm and then activates the enzyme necessary for the activation of transcription factors
• D. Binding of hormone to the cytoplasmic receptor that initiates the production of the second messenger which activates enzymes that further transcription factors

Answer 1

The correct option is A Binding of hormone to the cytoplasm receptor and the complex binds to hormone response element on DNA within promoter DNA

Steroid hormones, being hydrophobic molecules, diffuse freely into all cells and act within the cell. Steroid hormones secreted by adrenal cortex, ovaries, and testes do not utilize the second messenger to exert their influence. Steroid hormones enter the cytoplasm of a target cell and bind with specific receptor proteins (mobile). Hormone-receptor complex than diffuses into the nucleus and activates specific genes to form a new protein. This protein carries out the specific response for a particular steroid hormone.