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Question

The solubility of protein is influenced by

A
Concentration of solute
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B
Concentration of solvent
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C
pH
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D
None of the above
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Solution

The correct option is C pH
Proteins can be either positively charged or negatively charged based on pH conditions. When the positive and negative charges on the protein are equal, the net charge is zero. The characteristic pH of a solution at which the net charge on the protein is zero i.e. positive and negative charges are equal is called isoelectric point (pH). At isoelectric point, protein is least soluble. If there is a charge at the protein surface, the protein interacts with water, rather than with other protein molecules. This charge makes it more soluble. Thus the solubility of the protein is influenced by pH. Thus the correct answer is option C.

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