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Question

The terminalization occurs during

A
Leptotene through diplotene
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B
Pachytene through diplotene
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C
Zygotene through pachytene
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D
Diplotene through metaphase
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Solution

The correct option is D Diplotene through metaphase
During diplotene phase, the two homologous chromosomes begin to migrate apart as the 'synaptonemal complex' disintegrates between the two chromosomal arms and they begin to repel one another. This allows the two chromosome to move apart, held only by the chiasma. Whilst this process occurs the chromosome begin to uncoil, contrary to the natural progression of prophase, however they are still coiled enough to allow a distinct image of a chiasma formation under a microscope. The chiasma move towards the end of the chromatids in a process known as terminalization.

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