Question

The type of chromosomal aberration indicated in the diagram shows

• A. Interstitial translocation
• B. Reciprocal translocation
• C. Pericentric inversion
• D. Paracentric inversion
• E. Interstitial deletion

Answer 1

Answer: (C)

Pericentric inversion

Inversion is a chromosomal mutation where a segment of a chromosome is reversed end to end. It occurs by the introduction of breakage in a single chromosome, its rotation by l80${}^o$ followed by its reinsertion in the same location. If the inversion includes centromere, it is called a pericentric inversion. In the given image, the inverted segment includes centromere, Hence, the correct answer is C.