Ultrastructure of a cell organelle can best be studied through _____________.
A
Microdissection
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B
Electron microscope
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C
Phase contrast microscope
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D
Autoradiography
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Solution
The correct option is B Electron microscope
Microdissection refers to a variety of techniques where a microscope is used to assist in dissection.
Electron microscopy (EM) is a technique for obtaining high-resolution images of biological and non-biological specimens. It is used in biomedical research to investigate the detailed structure of tissues, cells, organelles, and macromolecular complexes.
Phase-contrast microscopy is an optical microscopy technique that converts phase shifts in the light passing through a transparent specimen to brightness changes in the image. Phase shifts themselves are invisible but become visible when shown as brightness variations.
Autoradiography is the bio-analytical technique, used to visualize the distribution of radioactively labeled substances with a radioisotope in a biological sample. It is a method by which radioactive material can be localized within a particular tissue, cell, cell organelles, or even biomolecules.
Hence the correct answer is (B).