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Question

What are founder mutations?


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Solution

Mutations:

  1. A mutation is a change in the nucleic acid sequence of an organism's genome, virus, or extrachromosomal DNA in biology.
  2. DNA or RNA can be found in viral genomes.
  3. Founder mutations are mutations detected in the DNA of individuals who were the original members of a population.
  4. The founder mutation is inherited from the gene carrier and passed down from generation to generation.
  5. For instance, inherited hemochromatosis, sickle cell anemia, etc.

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