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What are histones? What are their functions?

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Solution

Histones are the basic group of globular proteins that have a high content of basic amino acis, i.e., arginine and lysine. Histones forms the part of the chromosomal material in eukaryotic cells.

There are five types of histone proteins H1, H2A,H2B, H3, and H4. Four of them (H2A,H2B,H3andH4) occur in pairs to produce histone octamer called Nubody or core of nucleosome.

Functions Histones bear positively charged ends, that attract negetively charged strands of DNA.

Histones provides a medium around which DNA winds, and they play a vital role in gene regulation, as they act as gene repressor. They form the chromatin material and provide stability as are not coagulated by heat.


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