Question

What are the phases of Receptor-mediated endocytosis for Cholesterol uptake?

Answer 1

The several steps in receptor-mediated endocytosis for cholesterol uptake are as follows:

1. Receptor binding and activation.
2. Coated pit development.
3. Budding of Clathrin-Coated Vesicles.
4. Vesicle uncoating.
5. Other vesicles and early endosomes are connected.
6. Late endosomes or CURL are created. (CURL) Compartment for Ligand and Receptor Uncoupling.
7. Receptors are recycled to the cell's surface, and lysosomes and transport vesicles are combined.
8. breakdown of LDL results in the release of cholesterol.