The negative feedback loop or inhibitory loop includes 4 components like stimulus, sensor, control center, and effector.
It is a type of self-regulating system.
In a negative feedback loop, increased output from the system inhibits future production by the system.
The body reduces the number of certain proteins or hormones it creates when its levels get too high.
The negative feedback loops that direct the hypothalamic-pituitary axis include –
Short-loop feedback: pituitary hormones cause negative feedback which can suppress the secretion and/or synthesis of similar hypothalamic hormones.
Long loop feedback: hormones from peripheral endocrine glands can apply feedback control on the anterior pituitary and hypothalamus. Usually, this feedback is negative.