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Question

What happens in Hamburger shift?

A
HCO3 ions move out from plasma and Cl ions enter into RBC
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B
CO3 ions move out from plasma and Cl ions enter into RBC
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C
H+ ions move out from plasma and Cl ions enter into RBC
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D
HCO3 ions move out from plasma and H+ ions enter into RBC
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Solution

The correct option is A HCO3 ions move out from plasma and Cl ions enter into RBC
Chloride shift is also known as the Hamburger phenomenon, named after Hartog Jacob Hamburger. It is a process which occurs in a cardiovascular system and refers to the exchange of bicarbonate (HCO3 and Cl) across the membrane of red blood cells (RBCs) to maintain the neutrality of the plasma. HCO3 ions move out from plasma and Cl ions enter into RBC.

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