The correct option is A HCO–3 ions move out from plasma and Cl– ions enter into RBC
Chloride shift is also known as the Hamburger phenomenon, named after Hartog Jacob Hamburger. It is a process which occurs in a cardiovascular system and refers to the exchange of bicarbonate (HCO−3 and Cl−) across the membrane of red blood cells (RBCs) to maintain the neutrality of the plasma. HCO–3 ions move out from plasma and Cl– ions enter into RBC.