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Question

What hormones do the Leydig and Sertoli cells respond to?


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Solution

Hormones that Leydig and Sertoli cells respond to:

  1. Leydig cells and Sertoli cells respond to gonadotropins (LH and FSH) secreted by the anterior pituitary.
  2. Leydig cells have receptors for LH (luteinizing hormone).
  3. Sertoli cells have receptors for FSH (follicle-stimulating hormone).
  4. LH stimulates the secretion of androgens from Leydig cells.
  5. FSH stimulates Sertoli cells to secrete certain factors like androgen-binding protein involved in the spermiogenesis process.

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