In the nervous system, a synapse is a structure that permits a neuron to pass an electrical or chemical signal to another neuron or to the target efferent cell.
Each neuron generally produces just one type of classic neurotransmitter. Following their exocytosis from synaptic vesicles into the synaptic cleft, neurotransmitters bind to specific receptors on the plasma membrane of a postsynaptic cell, causing a change in its permeability to ions.