Coordination the process of controlling and regulating the activities of body metabolism by the nervous system and the endocrine system. For instance, the pituitary gland secretes the Thyroid Stimulating Hormone (TSH) upon the command of the hypothalamus which a neural part. The TSH regulates the activity of the thyroid gland to secrete the thyroxine which has an effect on the digestion, respiration and excretion.