In comparison to previous approaches, polymerase chain reaction tests may identify translocation-specific malignant cells directly on genomic DNA samples with a sensitivity of at least 10000-fold greater.
Molecular targets for cancer diagnosis and therapy are becoming available as a result of advances in biological sciences and technology.
The current surgical pathology categories for malignancy staging include anatomic characteristics (e.g., tumor-node-metastasis) and histology.
Microarrays and clustering algorithms are revealing a molecular variety across tumors that might lead to the formation of a new taxonomy with prognostic and therapeutic implications.