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Question

What is the difference between DNA damage and mutation?


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Solution

DNA damage:

DNA damage causes a change in the chemical structure of DNA and halts the replication process.

Mutation:

Mutation refers to the process where there is a change in the sequence of base pairs of DNA.

Differences between DNA damage and mutation:

DNA damageMutation
  1. DNA damage could be a disruption or chemical addition to a base of DNA.
  1. Mutations results due to environmental factors referred to as mutagens.

2. Most damage to DNA is repaired by removal of the damaged bases followed by resynthesis of the excised region.

2. Mutations may be spontaneous in nature.

3. Example: Alkylating agents.

3. Example: Down syndrome.


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