Question

What is the difference between histones and nucleosomes?

Answer 1

1. Histones are the proteins which are involved in the organization of the genetic material in the chromosome.
2. The nucleosome is a bead-like structure, containing approximately 200 base pairs.

Histones	Nucleosome
1. These are negatively charged proteins involved in the organization of the nucleosome.	1. These are the spherical structures formed when positively charged DNA strand is wrapped around a negatively charged histone octamer.
2. Histones are the unit of a nucleosome.	2. Nucleosomes are the unit of a chromatin thread.
3. Histone proteins come together and form an octamer.	3. Nucleosomes come together and form the chromatin thread ultimately forming the chromosomes.