Question

What is the function of Sertoli cells and Leydig cells?

Answer 1

Sertoli cells:

1. Sertoli cells are sometimes known as testicular "nurse cells" or "mother cells."
2. It is a component of a seminiferous tubule that aids in the process of spermatogenesis or the generation of sperm.

Functions of Sertoli cells:

1. It nourishes the growing sperm cells during spermatogenesis.
2. These cells function as phagocytes, consuming the cytoplasm left behind during spermatogenesis.
3. Inhibin, aromatase binding protein, and anti-mullerian hormone are all secreted by these cells.
4. They constitute the blood-testis barrier, which prevents undesired chemicals and germs from passing through.

Leydig cells:

1. Leydig cells are also known as Leydig interstitial cells.
2. They are located in the testicle near the seminiferous tubules.
3. Leydig cells feature a polyhedral structure, a big conspicuous nucleus, and eosinophilic cytoplasm.
4. They also feature a large number of lipid-filled vesicles.

Functions of Leydig cells

1. They produce androgens, which are hormones.
2. Androgens are steroid hormones that include testosterone, androstenedione, and dehydroepiandrosterone (DHEA).
3. The enzyme desmolase actively converts androstenedione and DHEA into testosterone.
4. Androgens are crucial in the development of secondary sexual characteristics throughout puberty, such as facial hair growth, sexual behavior, desire, and so on.
5. The parenchyma of the testis is formed by the seminiferous tubules.