Question

What is the smallest enzyme in the human body?

Answer 1

Smallest Enzyme : 4-Oxalocrotonate tautomerase

1. 4-Oxalocrotonate tautomerase is found to be smallest enzyme till now.
2. 4-Oxalocrotonate tautomerase is an enzyme that converts 2-hydroxymuconate to the αβ-unsaturated ketone, 2-oxo-3-hexenedioate.
3. This enzyme forms part of a bacterial metabolic pathway that catabolizes toluene, o-xylene, 3-ethyltoluene, and 1,2,4-trimethylbenzene into intermediates of the citric acid cycle by the process of oxidation.
4. This enzyme has monomeric size of just 62 amino acid residues making it one of the smallest enzyme subunits known till date.