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Question

What is the wobble effect?


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Solution

Wobble effect:

  1. The Wobble Hypothesis describes how one amino acid can be coded for by several codons.
  2. The third nucleotide in a codon is referred to as the wobble position.
  3. There are two main properties of this nucleotide.
  4. The cognate tRNA's binding to a codon in an mRNA is substantially more "loose" in the codon's third position.
  5. The third codon position can now accommodate a variety of non-Watson–Crick base pairings.

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