The Mammalian orthoreovirus (MRV) is a double stranded RNA virus. It is a part of the family Reoviridae, as well as the subfamily Spinareoviridae. As seen in the name, the Mammalian Ortheoreovirus infects numerous mammalian species and vertebrates which serve as natural hosts. Some diseases that occur as a result of this virus or are associated with this virus include mild upper respiratory illness, and gastrointestinal illness. Examples of these are: upper respiratory tract syndromes, gastroenteritis (stomach flu), biliary artesia, obstructive hydrocephalus, jaundice, alopecia, conjunctivitis, and ‘oily hair.