Chromaffin cells are the neuroendocrine cells found in the medulla of the adrenal glands.
Chromaffin cells are named for the granules within the cells that darken after exposure to chromium salts.
The chromaffin cells are derived from neural crest cells and distinctly differentiated into two types of cells, epinephrine (E) (adrenaline)-storing and norepinephrine (NE) (noradrenaline)-storing cells.
Chromaffin cells (CCs) of the adrenal gland produce the catecholamines such as epinephrine and norepinephrine.
It helps to coordinate the body for "fight-or-flight" responses due to fear, stress, or conflict.
Adrenal chromaffin cells contain many neuropeptides that regulate adrenocortical steroid production in many species.
Chromaffin cells are stimulated by the sympathetic nervous system in response to stress or emergency situations.
