Question

What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor:

• A. In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.
• B. Enterokinase will not be released from the duodenal mucosa and so trypsinogen is not converted to trypsin.
• C. Gastric juice will be deficient in chymosin.
• D. Gastric juice will be deficient in pepsinogen.

Answer 1

The correct option is A In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.

Parietal cells (also known as the oxyntic cells) secrete hydrochloric acid (HCl). HCl is responsible for activating the inactive pepsinogen into pepsin.