Question

Where do substrate-level phosphorylation and oxidative phosphorylation occur?

Answer 1

Oxidative phosphorylation

1. Oxidative phosphorylation occurs in the mitochondria in the electron transport chain.
2. Transferring energy from a higher-energy product to a lower-energy product (phosphate group attached or not).
3. This mechanism transfers a phosphoryl (PO3) group from another phosphorylated substance to ADP or GDP using some of the released chemical energy, the Gibbs free energy.
4. It's found in the citric acid cycle and glycolysis. In the process of substrate-level phosphorylation, oxidation and phosphorylation are not connected,

Substrate-level phosphorylation, oxidation, and phosphorylation

1. Reactive intermediates are most typically obtained in the course of oxidation events in catabolism.
2. Phosphorylation provides a faster, less efficient source of ATP that is not dependent on external electron acceptors.
3. The substrate level phosphorylation occurs in the cytoplasm as well as mitochondria at the time of glycolysis and Krebs cycle, respectively.
4. Human erythrocytes, which lack mitochondria, and oxygen-depleted muscle are examples of this.