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Question

Which chromosomal mutation is being shown in the diagram?
479499.jpg

A
Deletion
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B
Duplication
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C
Nondisjunction
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D
Inversion
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E
Translocation
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Solution

The correct option is A Inversion
Removal of one or more nucleotide bases to the DNA segment is known as deletion. Duplication is the presence of extrachromosomal segment which is attached to the normal homologous chromosome causing duplication of the set of genes in the same chromosome. Nondisjunction is the failure of separation of sister chromatids or homologous chromosomes during anaphase. Inversion is a chromosomal mutation in which a chromosome is broken at two places. The resulting piece of DNA is reversed and re-ligated into the chromosome. Exchange of chromosomal segment between two nonhomologous chromosomes is called reciprocal translocation. In the given image, AB”CDE”FGH is mutated to AB”EDC”FGH which means that segment “CDE” is inverted to “EDC”.
Therefore, the correct answer is option D.

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