Question

Which enzyme is responsible for conversion of norepinephrine to epinephrine?

• A. Catecholamine -O- methyl transferase
• B. Phenylalanine -N- methyltransferase
• C. DOPA carboxylase
• D. Monoamine oxidase

Answer 1

The correct option is B Phenylalanine -N- methyltransferase

• Phenylethanolamine N-methyltransferase (PNMT) is an enzyme found primarily in the adrenal medulla that converts norepinephrine (noradrenaline) to epinephrine (adrenaline).
• It is also expressed in small groups of neurons in the human brain. Hence, Phenylalanine -N- methyltransferase enzyme is responsible for the conversion of norepinephrine to epinephrine.

So, the correct answer is ' enzyme is responsible for conversion of norepinephrine to epinephrine'.