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Question

Which gas from the following will mix with haemoglobin of blood and affect the oxygen supply to various parts of body?

A
CO2
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B
NO
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C
CO
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D
SO2
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Solution

The correct option is C CO
The binding of oxygen is affected by molecules such as carbon monoxide (CO). CO competes with oxygen at the heme binding site. Haemoglobin binding affinity for CO is 250 times greater than its affinity for oxygen, which means that small amounts of CO dramatically reduce the ability of haemoglobin to transport oxygen. Since CO is a colourless, odourless and tasteless gas, and poses a potentially fatal threat, detectors have become commercially available to warn of dangerous levels in residences. When haemoglobin combines with CO, it forms a very bright red compound called carboxyhaemoglobin.

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